{"id":420,"date":"2025-06-02T22:52:58","date_gmt":"2025-06-02T13:52:58","guid":{"rendered":"https:\/\/otsuka-cl.com\/blog\/?p=420"},"modified":"2025-10-19T01:20:40","modified_gmt":"2025-10-18T16:20:40","slug":"%e6%bd%b0%e7%98%8d%e6%80%a7%e5%a4%a7%e8%85%b8%e7%82%8e%e3%81%ae%e6%b2%bb%e7%99%82%e7%9b%ae%e6%a8%99","status":"publish","type":"post","link":"https:\/\/otsuka-cl.com\/blog\/?p=420","title":{"rendered":"\u6f70\u760d\u6027\u5927\u8178\u708e\u306e\u6cbb\u7642\u76ee\u6a19 -UC\u306b\u4eba\u751f\u306e\u90aa\u9b54\u3092\u3055\u305b\u308b\u306a"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">\u6f70\u760d\u6027\u5927\u8178\u708e\uff08ulcerative colitis\uff1aUC\uff09\u306e\u6cbb\u7642\u306f\u3001\u6642\u4ee3\u3068\u3068\u3082\u306b\u5927\u304d\u304f\u5909\u9077\u3057\u3066\u304d\u307e\u3057\u305f<\/p>\n\n\n\n<p 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class=\"wp-block-heading\">UC\u6cbb\u7642\u7a76\u6975\u306e\u76ee\u7684-UC\u306b\u4eba\u751f\u306e\u90aa\u9b54\u3092\u3055\u305b\u308b\u306a\uff01<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u300e<strong>\u76ee\u6a19\uff1d\u76ee\u7684\u3092\u9054\u6210\u3059\u308b\u305f\u3081\u306b\u8a2d\u3051\u305f\u6307\u6a19<\/strong>\u300f\u3067\u3059\u306e\u3067\u3001\u307e\u305a\u76ee\u7684\u3092\u660e\u78ba\u306b\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u308f\u305f\u3057\u306eUC\u6cbb\u7642\u306e\u76ee\u7684\u306f\u3001\u3068\u306b\u304b\u304fUC\u306b\u4eba\u751f\u306e\u90aa\u9b54\u3092\u3055\u305b\u306a\u3044\u3053\u3068\u3067\u3059<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">UC\u3068\u3044\u3046\u75c5\u6c17\u306f\u73fe\u5728\u306e\u3068\u3053\u308d\u6cbb\u308b\u75c5\u6c17\u3067\u306f\u306a\u304f\u3001\u653e\u3063\u3066\u304a\u304f\u3068\u826f\u304f\u306a\u3063\u305f\u308a\uff08\u5bdb\u89e3\uff09\u3001\u60aa\u304f\u306a\u3063\u305f\u308a\uff08\u518d\u71c3\uff09\u3092\u7e70\u308a\u8fd4\u3057\u307e\u3059<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3057\u304b\u3082\u3001\u305d\u308c\u304c\u3044\u3064\u3084\u3063\u3066\u304f\u308b\u304b\u5206\u304b\u308c\u3070\u3044\u3044\u306e\u3067\u3059\u304c\u3001\u767a\u75c7\u3082\u518d\u71c3\u3082\u7a81\u7136\u306b\u3084\u3063\u3066\u304d\u307e\u3059<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7a81\u7136\u306e\u767a\u75c7\u306b\u5099\u3048\u308b\u3053\u3068\u306f\u51fa\u6765\u307e\u305b\u3093\u304c\u3001\u3067\u304d\u308b\u9650\u308a\u65e9\u671f\u306b\u3001\u3057\u3063\u304b\u308a\u3068\u8a3a\u65ad\u3092\u3059\u308b\u3053\u3068\u306f\u51fa\u6765\u307e\u3059<\/p>\n\n\n\n<p 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class=\"wp-block-paragraph\">\u3053\u306e\u91cd\u8981\u306a\u76ee\u7684\u3092\u9054\u6210\u3059\u308b\u305f\u3081\u306e\u6307\u6a19\u304c\u3053\u308c\u304b\u3089\u6319\u3052\u308b\u76ee\u6a19\u306b\u306a\u308a\u307e\u3059<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u81e8\u5e8a\u7684\u5bdb\u89e3\u3068\u306f\uff1f-\u75c7\u72b6\u30bc\u30ed\u306e\u4e16\u754c\u3078<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u75c7\u72b6\u304c\u6cbb\u307e\u3063\u3066\u3044\u308b\u72b6\u614b\u3092\u81e8\u5e8a\u7684\u5bdb\u89e3\u3068\u547c\u3073\u3001\u3053\u308c\u304c\u307e\u305a\u7b2c\u4e00\u306e\u76ee\u6a19\u3067\u3042\u308b\u3053\u3068\u306f\u9593\u9055\u3044\u3042\u308a\u307e\u305b\u3093<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7c21\u5358\u306b\u8a00\u3046\u3068\u3001UC\u3092\u767a\u75c7\u3059\u308b\u524d\u3068\u540c\u3058\u6392\u4fbf\u72b6\u6cc1\uff08\u56de\u6570\u3084\u6027\u72b6\uff09\u306b\u306a\u308b\u3053\u3068\u3067\u3059<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">UC\u306f\u3001\u8179\u75db\u3001\u8840\u4fbf\u3084\u4e0b\u75e2\u3068\u3044\u3063\u305f\u65e5\u5e38\u751f\u6d3b\u3092\u9001\u308b\u3053\u3068\u304c\u56f0\u96e3\u306b\u306a\u308b\u75c7\u72b6\u304c\u73fe\u308c\u307e\u3059<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u306e\u307e\u307e\u306e\u72b6\u614b\u3067\u306f\u5916\u6765\u6cbb\u7642\u3092\u7d99\u7d9a\u3059\u308b\u3053\u3068\u304c\u56f0\u96e3\u306b\u306a\u3063\u3066\u3057\u307e\u3044\u307e\u3059\u306e\u3067\u3001\u307e\u305a\u306f\u75c7\u72b6\u3092\u843d\u3061\u7740\u304b\u305b\u308b\u3053\u3068\u304c\u91cd\u8981\u3067\u3059<\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p class=\"wp-block-paragraph\">\u4ee5\u4e0b\u306e\u5831\u544a\u3067\u306f\u3001\u60a3\u8005\u3055\u3093\u306e\u591a\u304f\u304c1\u9031\u9593\u4ee5\u5185\u306b\u85ac\u304c\u52b9\u3044\u3066\u304f\u308c\u308b\u3068\u671f\u5f85\u3057\u3066\u3044\u308b\u4e00\u65b9\u3001\u79c1\u305f\u3061\u533b\u5e2b\u5074\u304c2\u9031\u304b\u30894\u9031\u9593\u306b\u52b9\u3044\u3066\u304f\u308c\u308c\u3070\u3068\u601d\u3063\u3066\u304a\u308a\u3001\u5c11\u3057\u89e3\u96e2\u304c\u3042\u308b\u3053\u3068\u304c\u308f\u304b\u308a\u307e\u3059<br><\/p>\n<cite><a href=\"https:\/\/academic.oup.com\/crohnscolitis360\/article\/7\/2\/otaf014\/8109143\">uestionnaire Survey of Japanese Patients With Inflammatory Bowel Disease and Physicians on Shared Decision-Making in Advanced Therapy: A Web-Based PAIR Survey <\/a><\/cite><\/blockquote>\n\n\n\n<figure class=\"wp-block-image size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"512\" src=\"https:\/\/otsuka-cl.com\/blog\/wp-content\/uploads\/2025\/06\/otaf014_fig2-1024x512.jpeg\" alt=\"\" class=\"wp-image-426\" style=\"width:523px;height:auto\" srcset=\"https:\/\/otsuka-cl.com\/blog\/wp-content\/uploads\/2025\/06\/otaf014_fig2-1024x512.jpeg 1024w, https:\/\/otsuka-cl.com\/blog\/wp-content\/uploads\/2025\/06\/otaf014_fig2-300x150.jpeg 300w, https:\/\/otsuka-cl.com\/blog\/wp-content\/uploads\/2025\/06\/otaf014_fig2-768x384.jpeg 768w, https:\/\/otsuka-cl.com\/blog\/wp-content\/uploads\/2025\/06\/otaf014_fig2-1536x767.jpeg 1536w, https:\/\/otsuka-cl.com\/blog\/wp-content\/uploads\/2025\/06\/otaf014_fig2-2048x1023.jpeg 2048w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p 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class=\"wp-block-paragraph\">\u3082\u3061\u308d\u3093\u305d\u3053\u306b\u306f\u30ea\u30b9\u30af\u3068\u30d9\u30cd\u30d5\u30a3\u30c3\u30c8\u306e\u91cd\u8981\u306a\u517c\u306d\u5408\u3044\u304c\u3042\u308a\u307e\u3059\u304c\u30011\u9031\u9593\u3057\u304b\u5f85\u3066\u306a\u3044\u307b\u3069\u56f0\u3063\u3066\u3044\u308b\u65b9\u306b\u306f\u5373\u52b9\u6027\u306e\u3042\u308b\u304a\u85ac\u3092\u30011\u30f6\u6708\u306f\u5f85\u3066\u308b\u65b9\u306b\u306f\u5373\u52b9\u6027\u306f\u306a\u304f\u3066\u3082\u51fa\u6765\u308b\u3060\u3051\u5b89\u5168\u306a\u304a\u85ac\u3092\u9078\u629e\u3057\u307e\u3059<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u63d0\u4f9b\u3067\u304d\u308b\u9078\u629e\u80a2\u304c\u591a\u3044\u307b\u3069\u60a3\u8005\u3055\u3093\u306e\u30cb\u30fc\u30ba\u306b\u5fdc\u3048\u308b\u5e45\u3082\u5e83\u304c\u308b\u3068\u8a00\u3048\u307e\u3059<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305d\u3046\u3044\u3046\u610f\u5473\u3067\u79c1\u305f\u3061\u306e\u3088\u3046\u306a\u708e\u75c7\u6027\u8178\u75be\u60a3\u3092\u5c02\u9580\u3068\u3057\u3066\u3044\u308b\u533b\u7642\u6a5f\u95a2\u306f\u91cd\u8981\u3060\u3068\u8003\u3048\u3066\u3044\u307e\u3059<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305d\u3057\u3066\u91cd\u8981\u306a\u3053\u3068\u304c\u3082\u3046\u4e00\u3064\u3042\u308a\u307e\u3059<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u81e8\u5e8a\u7684\u5bdb\u89e3\u3067\u6cbb\u7642\u3092\u3084\u3081\u3066\u3057\u307e\u3063\u305f\u308a\u3001\u6cb9\u65ad\u3057\u3066\u3057\u307e\u3046\u3068\u3001\u65e9\u671f\u306b\u518d\u71c3\u3059\u308b\u3053\u3068\u306b\u306a\u308a\u307e\u3059<\/strong><\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p class=\"wp-block-paragraph\">\u4f8b\u3048\u3070\u3001UC\u6cbb\u7642\u306e\u4e2d\u5fc3\u3067\u3042\u308b5-ASA(\u30a2\u30df\u30ce\u30b5\u30ea\u30c1\u30eb\u9178)\u88fd\u5264\u3067\u3059\u304c\u3001\u5341\u5206\u91cf\u3092\u4f7f\u7528\u3059\u308c\u30708\u5272\u8fd1\u304f\u306e\u60a3\u8005\u3067\u5bdb\u89e3\u306b\u9054\u3059\u308b\u3068\u3044\u3046\u5831\u544a\u304c\u3042\u308a\u307e\u3059<\/p>\n<cite><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20878425\/\">Clinical trial: Effects of an oral preparation of mesalazine at 4 g\/day on moderately active ulcerative colitis. A phase III parallel-dosing study <\/a><\/cite><\/blockquote>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p class=\"wp-block-paragraph\">\u4e00\u65b9\u3067\u3001\u5185\u670d\u9075\u5b88\u7387\u304c80 %\u672a\u6e80\u306b\u306a\u308b\u3068\u3001\u5bdb\u89e3\u7dad\u6301\u7387\u306f40 %\u7a0b\u5ea6\u306b\u306a\u3063\u3066\u3057\u307e\u3046\u3068\u3044\u3046\u5831\u544a\u3082\u3042\u308a\u307e\u3059<\/p>\n<cite><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/12543288\/\">Medication nonadherence and the outcomes of patients with quiescent ulcerative colitis <\/a><\/cite><\/blockquote>\n\n\n\n<p class=\"wp-block-paragraph\">\u6cbb\u7642\u3092\u7d99\u7d9a\u3059\u308b\u3053\u3068\u304c\u3044\u304b\u306b\u91cd\u8981\u304b\u304a\u308f\u304b\u308a\u9802\u3051\u305f\u3067\u3057\u3087\u3046\u304b<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305d\u3057\u3066\u3001\u5b9a\u671f\u7684\u306a\u691c\u67fb\u3067\u518d\u71c3\u3092\u4e88\u6e2c\u3059\u308b\u3053\u3068\u3082\u91cd\u8981\u3067\u3059\u304c\u3001\u3055\u3089\u306a\u308b\u9ad8\u898b\u3067\u3042\u308b\u5185\u8996\u93e1\u7684\u5bdb\u89e3\u306b\u7e4b\u304c\u3063\u3066\u3044\u304f\u308f\u3051\u3067\u3059<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u5185\u8996\u93e1\u7684\u5bdb\u89e3\u304c\u9375\uff01\u7c98\u819c\u306e\u72b6\u614b\u3067\u307f\u308b\u771f\u306e\u5bdb\u89e3<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u7c98\u819c\u6cbb\u7652<\/strong>\u3068\u3044\u3046\u6982\u5ff5\u304c1984\u5e74\u306bKorelitz\u3089\u306e\u8ad6\u6587\u3067\u521d\u3081\u3066\u767b\u5834\u3057\u3001\u5f53\u521d\u306f\u7d44\u7e54\u5b66\u7684\u708e\u75c7\u306e\u6539\u5584\u3092\u6307\u3059\u3082\u306e\u3068\u3055\u308c\u3066\u3044\u307e\u3057\u305f<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3057\u304b\u3057\u3001\u660e\u78ba\u306a\u5b9a\u7fa9\u304c\u306a\u3044\u72b6\u614b\u304c\u7d9a\u3044\u305f\u3082\u306e\u306e\u3001\u591a\u304f\u306e\u81e8\u5e8a\u8a66\u9a13\u304c\u9032\u3080\u306b\u3064\u308c\u3066\u73fe\u5728\u306e\u300c<strong>\u5185\u8996\u93e1\u7684\u5bdb\u89e3<\/strong>\u300d\u3068\u307b\u307c\u540c\u7fa9\u306e\u3082\u306e\u3068\u3057\u3066\u8a8d\u8b58\u3055\u308c\u308b\u3088\u3046\u306b\u306a\u308a\u307e\u3057\u305f<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u308f\u305f\u3057\u305f\u3061\u306b\u306f\u5185\u8996\u93e1\u7684\u5bdb\u89e3\u306e\u65b9\u304c\u3057\u3063\u304f\u308a\u304d\u307e\u3059\u304c\u3001\u60a3\u8005\u3055\u3093\u306b\u306f\u300e\u7c98\u819c\u306e\u72b6\u614b\u304c\u304d\u308c\u3044\u306b\u306a\u308b\u304b\u3089\u7c98\u819c\u6cbb\u7652\u300f\u306e\u65b9\u304c\u5206\u304b\u308a\u3084\u3059\u3044\u3068\u601d\u3044\u307e\u3059<\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p class=\"wp-block-paragraph\">\u7c98\u819c\u6cbb\u7652\u304cUC\u306e\u9577\u671f\u7ba1\u7406\u306b\u679c\u305f\u3059\u5f79\u5272\u306f\u3001\u30ce\u30eb\u30a6\u30a7\u30fc\u306eIBSEN study\u306b\u3088\u3063\u3066\u660e\u3089\u304b\u306b\u3055\u308c\u3066\u3044\u307e\u3059<\/p>\n<cite><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17681162\/\">Mucosal healing in inflammatory bowel disease: results from a Norwegian population-based cohort <\/a><\/cite><\/blockquote>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u306e\u7814\u7a76\u3067\u306f\u3001\u6cbb\u7642\u958b\u59cb\u304b\u30891\u5e74\u5f8c\u306b\u7c98\u819c\u6cbb\u7652\u304c\u9054\u6210\u3067\u304d\u305f\u60a3\u8005\u7fa4\u306f\u3001\u672a\u9054\u6210\u306e\u60a3\u8005\u7fa4\u3068\u6bd4\u3079\u3066\u75be\u60a3\u6d3b\u52d5\u6027\u304c\u4f4e\u4e0b\u3057\u3001\u3055\u3089\u306b\u306f\u624b\u8853\u7387\u3082\u6291\u5236\u3055\u308c\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u307e\u3057\u305f<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u306e\u7d50\u679c\u306f\u3001\u7c98\u819c\u6cbb\u7652\u306e\u9054\u6210\u304c\u9577\u671f\u7684\u306a\u4e88\u5f8c\u306e\u6539\u5584\u306b\u76f4\u7d50\u3059\u308b\u3053\u3068\u3092\u88cf\u4ed8\u3051\u3066\u3044\u307e\u3059<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5185\u8996\u93e1\u7684\u5bdb\u89e3\u304c\u3061\u3083\u3093\u3068\u9054\u6210\u3067\u304d\u3066\u3044\u308b\u304b\u3069\u3046\u304b\u3092\u78ba\u8a8d\u3059\u308b\u306b\u306f\u3001\u30bf\u30a4\u30df\u30f3\u30b0\u3088\u304f\u5185\u8996\u93e1\u691c\u67fb\u3092\u53d7\u3051\u308b\u3053\u3068\u304c\u5927\u4e8b\u3067\u3059<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u65e9\u3081\u306b\u75c5\u6c17\u306e\u72b6\u614b\u3092\u628a\u63e1\u3057\u3066\u3001\u5fc5\u8981\u306a\u6cbb\u7642\u306e\u8abf\u6574\u3092\u3059\u308b\u3053\u3068\u3067\u3001\u3088\u308a\u9577\u304f\u5065\u5eb7\u306a\u72b6\u614b\u3092\u4fdd\u3066\u308b\u53ef\u80fd\u6027\u304c\u9ad8\u307e\u308a\u307e\u3059<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3067\u3059\u306e\u3067\u3001\u75c7\u72b6\u304c\u843d\u3061\u7740\u3044\u3066\u3044\u3066\u3082\u5927\u8178\u30ab\u30e1\u30e9\u3092\u4e00\u5e74\u306b\u4e00\u56de\u306f\u53d7\u3051\u3066\u9802\u304f\u3053\u3068\u304c\u91cd\u8981\u306a\u3093\u3067\u3059<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u51fa\u6765\u308b\u304b\uff01\uff1f\u5185\u8996\u93e1\u7684\u5bdb\u89e3-\u53ef\u80fd\u6027\u3078\u306e\u6311\u6226<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u3067\u306f\u3001\u81e8\u5e8a\u7684\u5bdb\u89e3\u3060\u3051\u3069\u5185\u8996\u93e1\u7684\u5bdb\u89e3\u3067\u306f\u306a\u3044\u4eba\u306b\u3001\u3072\u305f\u3059\u3089\u306b\u5185\u8996\u93e1\u7684\u5bdb\u89e3\u3092\u76ee\u6307\u3057\u3066\u6cbb\u7642\u3092\u5f37\u5316\u3057\u3066\u3044\u304f\u3053\u3068\u304c\u3088\u3044\u306e\u3067\u3057\u3087\u3046\u304b\uff1f<\/p>\n\n\n\n<p 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class=\"wp-block-paragraph\">\u308f\u305f\u3057\u305f\u3061\u3082\u60a3\u8005\u3055\u3093\u3068\u4e00\u7dd2\u306b\u60a9\u307e\u3055\u305b\u3066\u9802\u304d\u307e\u3059<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u60a3\u8005\u3068\u5171\u306b\u6b69\u3080-UC\u6cbb\u7642\u306e\u30d1\u30fc\u30c8\u30ca\u30fc\u30b7\u30c3\u30d7<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u8272\u3005\u3068\u66f8\u3044\u3066\u304d\u307e\u3057\u305f\u304c\u3001\u7d50\u5c40\u306e\u3068\u3053\u308d\u76ee\u6a19\u306f\u8981\u76f8\u8ac7\u3067\u3059<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u308c\u3092\u79c1\u305f\u3061\u306e\u7528\u8a9e\u3067\u8a00\u3046\u3068\u3001<em>SDM<\/em>\uff08Shared Decision Making\u30fb\u5171\u540c\u610f\u601d\u6c7a\u5b9a\uff09\u3068\u8a00\u3044\u307e\u3059<\/p>\n\n\n\n<p 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class=\"wp-block-paragraph\">UC\u6cbb\u7642\u306b\u7d42\u308f\u308a\u306f\u3042\u308a\u307e\u305b\u3093\u306e\u3067\u3001\u60a3\u8005\u3055\u3093\u3068\u4e00\u7dd2\u306b\u8003\u3048\u3066\u884c\u304d\u305f\u3044\u3068\u601d\u3044\u307e\u3059<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u6f70\u760d\u6027\u5927\u8178\u708e\uff08ulcerative colitis\uff1aUC\uff09\u306e\u6cbb\u7642\u306f\u3001\u6642\u4ee3\u3068\u3068\u3082\u306b\u5927\u304d\u304f\u5909\u9077\u3057\u3066\u304d\u307e\u3057\u305f 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